کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8471931 1550143 2006 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Le point sur les anticorps autorisés en imagerie et en immunothérapie
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
پیش نمایش صفحه اول مقاله
Le point sur les anticorps autorisés en imagerie et en immunothérapie
چکیده انگلیسی
Since 1975, when Kohler and Milstein developed a procedure to efficiently produce monoclonal antibodies, these molecules gave rise to huge hopes as reagents for imaging or therapy, just like the magic bullets imagined by Paul Ehrlich in the beginning of the twentieth century. However it took numerous years and lots of failures before the concept monoclonal antibodies became a reality in terms of treatment. The development of recombinant antibody technologies and the first commercial successes have changed the way we think about antibodies as medicines, and one can reasonably expects an explosive growth of antibodies approved for medical use. This review gives an update on the key technologies and on antibodies available at this time.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Immuno-analyse & Biologie Spécialisée - Volume 21, Issue 5, October 2006, Pages 255-263
نویسندگان
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