Prise en charge d'une hyperandrogénie chez l'adolescente

Hyperandrogenism is one of the most common disorder in women with a prevalence estimated between 5 and 10 percent. Due to androgens excess from ovaries, more rarely adrenal gland, the first symptoms usually begin around menarche. This is a complex disorder and a large spectrum of phenotype is observed because presenting signs and symptoms are heterogeneous and diagnosis is not easy because clinical manifestation is often banal. Hirsutism and acné are the main clinical manifestations. They are associated with irregular menstrual cycles and/or overweight. The precocious management is necessary to prevent consequences on dysovulation and métabolic syndrome. In other hand, long term glucocorticoid treatment to reduce elevated levels of andrenal sex steroids is necessary in patients with 21 Hydroxylase deficiency.