کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8472162 1550303 2007 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The deficiency of C1 inhibitor and its treatment
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
پیش نمایش صفحه اول مقاله
The deficiency of C1 inhibitor and its treatment
چکیده انگلیسی
In this article, we review the traditional therapies of hereditary angioedema (HAE) that have been used for several years. Some of these therapies were proposed before the definition of the underlying defect and the understanding of the pathogenesis of the disease. We also describe new compounds under investigation at present as potential therapies for HAE. Two of these new therapies (a plasma-kallikrein inhibitor and a bradykinin B(2)-receptor antagonist) have been developed based on the understanding that the pathogenesis of symptoms was mainly due to kallikrein activation and bradykinin release.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Immunobiology - Volume 212, Issues 4–5, 26 June 2007, Pages 325-331
نویسندگان
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