Roles of Wnt8a during formation and patterning of the mouse inner ear

► Loss of Fgf3 leads to absence of Wnt8a expression during murine inner ear formation. ► Wnt8a mouse mutants show no defects during inner ear development. ► Double mutants for Wnt8a and Fgf3 show reduced expression of Fgf15. ► Double mutants for Wnt1 and Wnt8a show defects during dorsal morphogenesis of the inner ear.