A novel Anxa2-interacting protein Ebp1 inhibits cancer proliferation and invasion by suppressing Anxa2 protein level

- A total of 312 proteins were identified as candidate Anxa2 interacting partners.
- We identified Ebp1 as a novel binding protein of Anxa2.
- Anxa2 and Ebp1 may function as “hubs” in the Anxa2 interaction network.
- Ebp1 binds to Anxa2 and regulates proliferation and invasion of breast cancer cells.