Erythropoietin improves insulin resistance via the regulation of its receptor-mediated signaling pathways in 3T3L1 adipocytes

► Erythropoietin reduces insulin resistance in mature adipocytes. ► Erythropoietin regulates adipocytokine profile. ► Erythropoietin enhances insulin signaling transduction. ► Improved insulin resistance is dependant of its specific receptor.