Endocrine control of mucosal immunity in the female reproductive tract: Impact of environmental disruptors

► We examine innate and adaptive immunity in the female reproductive tract (FRT). ► We define the role of sex hormones in regulating FRT mucosal immunity. ► Endocrine disruptors alter disease susceptibility in the FRT. ► Reproductive health depends on understanding how endocrine disruptors work. ► Information about endocrine disruptors will increase reproductive health.