Functional interaction of fibroblast growth factor-8, bone morphogenetic protein and estrogen receptor in breast cancer cell proliferation

► FGF-8 facilitates ER-positive breast cancer cell proliferation. ► FGF-8 enhances estrogenic action but suppresses BMPR signaling in breast cancer cells. ► Suppression of FGF-8 could be a therapeutic strategy for estrogen-responsive breast cancer.