کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8480619 1551388 2014 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Shaping up to divide: Coordinating actin and microtubule cytoskeletal remodelling during mitosis
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
پیش نمایش صفحه اول مقاله
Shaping up to divide: Coordinating actin and microtubule cytoskeletal remodelling during mitosis
چکیده انگلیسی
Cell division requires the wholesale reorganization of cell architecture. At the same time as the microtubule network is remodelled to generate a bipolar spindle, animal cells entering mitosis replace their interphase actin cytoskeleton with a contractile mitotic actomyosin cortex that is tightly coupled to the plasma membrane - driving mitotic cell rounding. Here, we consider how these two processes are coordinated to couple chromosome segregation and cell division. In doing so we explore the relative roles of cell shape and the actin cortex in spindle morphogenesis, orientation and positioning.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seminars in Cell & Developmental Biology - Volume 34, October 2014, Pages 109-115
نویسندگان
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