کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8480999 | 1551409 | 2018 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Neurochemical characteristics of calbindin-like immunoreactive coeliac-cranial mesenteric ganglion complex (CCMG) neurons supplying the pre-pyloric region of the porcine stomach
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کلمات کلیدی
StgENSCBPsCARTRTXPGP 9.5like immunoreactiveSCGVIPCalbindin-D28kDRGPBSsuperior cervical ganglion - ganglion برتر گردن رحمSOM - WHOImmunohistochemistry - ایمونوهیستوشیمیtyrosine hydroxylase - تیروزین هیدروکسیلازPig - خوکGastrointestinal - دستگاه گوارشresiniferatoxin - رزینیفراتوکسینFast Blue - سریع آبیSomatostatin - سوماتواستاتینenteric nervous system - سیستم عصبی روده ایLenk - لهنSubstance P - ماده PPhosphate-buffered saline - محلول نمک فسفات با خاصیت بافریcalcium-binding proteins - پروتئین های مرتبط با کلسیمprotein gene-product 9.5 - پروتئین ژن محصول 9.5vasoactive intestinal peptide - پپتید روده روده ایcalbindin - کلبیندینGal - گالGalanin - گالانینdorsal root ganglia - گانگلیس ریشه پشتیStellate ganglion - گانگلیون ستاره ایceliac ganglion - گانگلیون سلیاک
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم کشاورزی و بیولوژیک (عمومی)
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
The present study was designed to determine the distribution, morphology and co-localization of calbindin-D28k (CB) with other neuroactive substances in the coeliac-cranial mesenteric ganglion complex (CCMG) neurons supplying the prepyloric region of the porcine stomach. In all animals, a median laparotomy was performed and the fluorescent retrograde neuronal tracer Fast Blue was injected into the wall of the stomach prepyloric area. On the 28th day, all animals were euthanized and the CCMG complexes were then collected and processed for double-labelling immunofluorescence for CB and tyrosine hydroxylase (TH), galanin (GAL), somatostatin (SOM), leu 5-enkephalin (LENK), vasoactive intestinal peptide (VIP), substance P (SP) and cocaine- and amphetamine-regulated transcript peptide (CART), Immunohistochemistry revealed that 8.27 ± 0.51% of FB-positive neurons expressed CB-like immunoreactivity. Furthermore, CB co-localized with TH, GAL and SOM in retrogradely labelled cell bodies, whereas CART, LENK, VIP and SP were detected only in nerve terminals surrounding FB+/CB+ neurons. The presence of CB in the stomach-projecting neurons may indicate the contribution of CB in the sympathetic regulation of the stomach function. Furthermore, CB-LI neurons had a catecholaminergic character and co-localized with TH, GAL and SOM, which suggests multiple functions of this neuroactive substance in the CCMG neurons supplying the porcine prepyloric area.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Tissue and Cell - Volume 50, February 2018, Pages 8-14
Journal: Tissue and Cell - Volume 50, February 2018, Pages 8-14
نویسندگان
Katarzyna Palus, MichaÅ Bulc, Marta Czajkowska, Bartosz MiciÅski, JarosÅaw CaÅka,