کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8526918 1557988 2018 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Novel triterpene saponins isolated from Clematis mandshurica and their inhibitory activities on NO production
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی طب مکمل و جایگزین
پیش نمایش صفحه اول مقاله
Novel triterpene saponins isolated from Clematis mandshurica and their inhibitory activities on NO production
چکیده انگلیسی
Four new triterpene saponins, mandshunosides F-I (1-4), together with five known compounds (5-9), were isolated from the roots and rhizomes of Clematis mandshurica. Their structures were elucidated on the basis of spectroscopic evidences and hydrolysis products. Bisdesmosidic saponin (3-9) showed modest suppression of NO production with the inhibition ratios in the range of 51.3%- 64.6% at 50 μmol·L−1, whereas monodesmosidic saponins with a free carboxyl group at C-28 (1 and 2) showed potent inhibitory activities with IC50 values being 12.7 and 8.3 μmol·L−1, respectively.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chinese Journal of Natural Medicines - Volume 16, Issue 2, February 2018, Pages 131-138
نویسندگان
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