کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8527303 | 1557996 | 2017 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Triterpenoid saponins from the roots of Cyathula officinalis and their inhibitory effects on nitric oxide production
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
طب مکمل و جایگزین
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Triterpenoid saponins from the roots of Cyathula officinalis and their inhibitory effects on nitric oxide production Triterpenoid saponins from the roots of Cyathula officinalis and their inhibitory effects on nitric oxide production](/preview/png/8527303.png)
چکیده انگلیسی
The present study was designed to investigate the chemical constituents of the roots of Cyathula officinalis. Compounds were isolated by silica gel, Sephadex LH-20, ODS column chromatography, and preparative HPLC. Their structures were determined on the basis of 1D and 2D NMR techniques, mass spectrometry, and chemical methods. One new oleanane-type triterpenoid saponin, 28-O-[α-L-rhamnopyranosyl-(1â3)-β-D-glucuronopyranosyl-(1â3)-β-D-glucopyranosyl] hederagenin (1), was isolated from the roots of Cyathula officinalis. The anti-inflammatory activities of the isolates were evaluated for their inhibitory effects against LPS-induced nitric oxide (NO) production in RAW 264.7 macrophages cells. Compounds 2, 4, and 6 exhibited moderate anti-inflammatory activities.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Chinese Journal of Natural Medicines - Volume 15, Issue 6, June 2017, Pages 463-466
Journal: Chinese Journal of Natural Medicines - Volume 15, Issue 6, June 2017, Pages 463-466
نویسندگان
Yun-Tao JIANG, Wen-Jing YAN, Chu-Lu QI, Ji-Qin HOU, Yan-Ying ZHONG, Hui-Jun LI, Hao WANG, Ping LI,