کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8542481 1561450 2013 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
LC-MS/MS analysis of tetracycline antibiotics in prawns (Penaeus monodon) from south India coastal region
موضوعات مرتبط
علوم پزشکی و سلامت داروسازی، سم شناسی و علوم دارویی فارماکولوژی، سم شناسی و اقلام دارویی (عمومی)
پیش نمایش صفحه اول مقاله
LC-MS/MS analysis of tetracycline antibiotics in prawns (Penaeus monodon) from south India coastal region
چکیده انگلیسی
The aim of the present study is to analyze the presence of tetracycline antibiotics (Tetracycline (TC), Oxytetracycline (OTC), Chlortetracycline (CTC) and Doxycycline (DOC)) in prawns (Penaeus monodon) obtained from the coastal region of southern India. LC-MS/MS was used for determination of tetracycline antibiotics. Separation was carried out by gradient elution technique using mobile phase A (0.1% formic acid in water) and mobile phase B (0.1% formic acid in methanol), at a flow rate of 400 μl/min and injection volume 20 μl. The % recoveries of analyzed drugs were in between 80 and 101. The results indicated that tetracycline antibiotics were not found in most of the samples. The samples collected from Andhra Pradesh and Karnataka were detected with oxytetracycline antibiotic but it was less than the maximum residual limit (MRL).
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Pharmacy Research - Volume 6, Issue 1, January 2013, Pages 48-52
نویسندگان
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