کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
856271 | 1470716 | 2015 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Combination of 3D Extruded-based Poly (ɛ-caprolactone) Scaffolds with Mesenchymal Stem/Stromal Cells: Strategy Optimization
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موضوعات مرتبط
مهندسی و علوم پایه
سایر رشته های مهندسی
مهندسی (عمومی)
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
This study uses a combination of 3D extruded-based biodegradable scaffolds and human bone marrow-derived mesenchymal stem/stromal cells to understand how scaffold properties can contribute for efficient cell seeding, proliferation and migration. Highly interconnected porous poly(ɛ-caprolactone) scaffolds were produced by a layer-by-layer extrusion. Two configurations were studied with larger (390 μm) or smaller pore size (190 μm) at the centre. MSC, seeded on the top centre of the scaffold surface, increased 5 folds after 13 days of cultivation for both configurations, allowing us to conclude that in this range of pore sizes pose no limitations for cell migration are observed.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Procedia Engineering - Volume 110, 2015, Pages 122-127
Journal: Procedia Engineering - Volume 110, 2015, Pages 122-127