Neurogenic bladder as a symptom of caudal regression syndrome

Caudal regression syndrome (CRS) is an ultra-rare congenital anomaly characterized by distal vertebral malformations usually coexisting with spinal cord malformations, neurological deficit in the lower limbs and neurogenic bladder. Its etiopathogenesis remains unclear. We report 2 children with CRS associated with neurogenic bladder. In the first patient, CRS was revealed during evaluation of recurrent urinary tract infections (UTIs). In the second one, CRS led to chronic kidney disease (CKD) as a result of patient's poor compliance.