Selective Chemosensing and Diagnostic Breathanalyzer

The study of a gas-selective, resistive-type, sensor technology to detect and quantitate nitric oxide (NO) in exhaled breath for diagnostic purposes is described here. The sensor and breathalyzer technology developed by our research group is presented as a tool for the personalized monitoring of the fraction of nitric oxide (FeNO) in exhaled breath, with the long term objective of prevention or control of airway diseases, such as asthma. FeNO is a known biomarker for measuring airway inflammation and it is shown here that the developed technology provides an effective and practical means to quantitate NO levels in breath-simulated samples in a relatively simple and noninvasive way. A sensor microsystem has been developed that quantifies the gas sensor response to generate an accurate measure of the NO concentration in a single exhaled breath.