Integrated Microfluidic Environment for Solid-state Nanopore Sensors

The micro- and nanotechnology based biosensing principles open up new possibilities towards the development and realisation of robust, user-friendly and cost-effective in-vitro diagnostic platforms. Furthermore, label-free and multi- analyte detection is envisioned to allow more accuracy and higher throughput in clinical diagnostic. The bioanalytical systems are expected to integrate the nanoscale transducers with interface chemistry, and bio-receptors as well as the microfluidics, control software and hardware. The final goal of this work is to develop nanopore based multi- parametric biosensing platform, applicable for label-free detection of blood marker proteins of cardiovascular symptoms.