کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8611451 | 1567219 | 2017 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Controle da hipnose na administração de propofol com base na estratégia de controle não linear
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
بیهوشی و پزشکی درد
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![عکس صفحه اول مقاله: Controle da hipnose na administração de propofol com base na estratégia de controle não linear Controle da hipnose na administração de propofol com base na estratégia de controle não linear](/preview/png/8611451.png)
چکیده انگلیسی
Continuous adjustment of Propofol in manual delivery of anesthesia for conducting a surgical procedure overburdens the workload of an anesthetist who is working in a multiâtasking scenario. Going beyond manual administration and Target Controlled Infusion, closedâloop control of Propofol infusion has the potential to offer several benefits in terms of handling perturbations and reducing the effect of interâpatient variability. This paper proposes a closedâloop automated drug administration approach to control Depth Of Hypnosis in anesthesia. In contrast with most of the existing research on anesthesia control which makes use of linear control strategies or their improved variants, the novelty of the present research lies in applying robust control strategy i.e. Sliding Mode Control to accurately control drug infusion. Based on the derived patient's model, the designed controller uses measurements from EEG to regulate DOH on Bispectral Index by controlling infusion rate of Propofol. The performance of the controller is investigated and characterized with real dataset of 8 patients undergoing surgery. Results of this in silico study indicate that for all the patients, with 0% overshoot observed, the steady state error lies in between ±5. Clinically, this implies that in all the cases, without any overdose, the controller maintains the desired DOH level for smooth conduction of surgical procedures.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brazilian Journal of Anesthesiology - Volume 67, Issue 2, MarchâApril 2017, Pages 122-130
Journal: Brazilian Journal of Anesthesiology - Volume 67, Issue 2, MarchâApril 2017, Pages 122-130
نویسندگان
Muhammad Ilyas, Ali Khaqan, Jamshed Iqbal, Raja Ali Riaz,