Study on Exposure Assessment Model of Dioxane in Shampoo

Setting dioxane in shampoo as the research object, exposure assessment of dioxane via skin route was studied. Scene simulation of dioxane exposure to human via skin was made after analysis of dioxane damage characteristics. Then the exposure assessment model of dioxane in shampoo via skin route was established and the concentration of dioxane was measured. The result shows that the concentration of dioxane is 7.213 mg/kg when the confidence level reaches to 95%, average daily absorbed dose is 9.913¥10-7 mg/(kg.d) and the cancer risk level of dioxane is 2.8914¥10-7/a.