Analgesic efficacy and safety of peri-operative pregabalin following radical cystectomy: A dose grading study

Peri-operative pregabalin at doses of 300 mg and 600 mg reduced postoperative opioid consumption and prolonged time to first request of analgesia in patients who underwent radical cystectomy, and a single preoperative dose of 600 mg is superior in analgesia to others, without serious side effects.