Fluorescence in situ hybridization of thyroid fine-needle aspiration biopsy distinguishes between neoplastic and non-neoplastic Hürthle cell lesions

Thyroid FNA biopsy can identify Hürthle cell proliferations; risk stratification based on morphology is difficult, however. FISH chromosomal evaluation of thyroid FNA biopsies is useful to distinguish neoplastic from non-neoplastic Hürthle cell proliferation.