کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8624391 | 1567959 | 2018 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Risk factors in securing successful surgical resection of oral squamous cell carcinoma
ترجمه فارسی عنوان
عوامل خطر در برداشتن جراحی موفقیت آمیز کارسینوم سلول سنگفرشی دهان
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کلمات کلیدی
سرطان دهان، سرطان سلولی فلسی، جراحی، درمان قبل از عمل،
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
بیوشیمی بالینی
چکیده انگلیسی
The purpose of this retrospective study was to analyze the factors that had a significant effect on securing a successful surgical resection (surgical margin) in oral cancer surgery. One hundred forty-eight consecutive patients who underwent planned radical resection of oral squamous cell carcinoma (SCC) were analyzed. Successful resection was judged if pathological examination of the surgical specimen revealed a clear surgical margin (no SCC within 5 mm, n = 116), while an unsuccessful resection was judged if there was a close and involved surgical margin (SCC within 5 mm, n = 21; and SCC at margin, n = 11). Univariate analyses showed that gender, age, and T-classification had significant influence on successful surgical resection. The results of multivariate logistic regression analysis showed that age (odds ratio [OR] = 1.042, 95% CI = 1.001-1.084), T-classification (OR = 1.656, 95% CI = 1.060-2.587), and the presence of preoperative treatment (OR = 2.868, 95% CI = 1.047-7.85) had significant effects on successful surgical resection. The results of this study suggested that successful resection of oral SCC was difficult in patients with either older age or advanced (T4) tumor. It is also suggested that preoperative therapy had a positive effect on securing a pathologically clear surgical margin.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Oral Science International - Volume 15, Issue 2, July 2018, Pages 56-60
Journal: Oral Science International - Volume 15, Issue 2, July 2018, Pages 56-60
نویسندگان
Yoshitaka Nakanishi, Shin-ichi Yamada, Rishiho Nishizawa, Tetsu Shimane, Takahiro Kamata, Takeshi Koike, Shinobu Uehara, Hiroshi Kurita,