Salivary tissue factor concentration and activity in patients with oral lichen planus

Impaired oxidant-antioxidant balance and inflammatory features of OLP might cause an increase in the salivary TF concentration and activity. As TF factor plays a critical role in inflammation progress, the use of an antioxidant agent in OLP may decrease the salivary TF concentration by decreasing oxidative stress. The findings of this study might represent a novel approach to OLP monitoring and treatment in terms of TF as the measurement of TF is easy and cost-effective.