کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8628752 1568703 2018 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
CXCL4 and CXCL4L1 in cancer
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی علوم غدد
پیش نمایش صفحه اول مقاله
CXCL4 and CXCL4L1 in cancer
چکیده انگلیسی
Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also important in the development and progression of cancer. CXCL4 and its non-allelic variant CXCL4L1 are two platelet-associated chemokines that have been attributed anti-tumoral activity as a result of their angiostatic potential and the chemotactic activity for anti-tumoral leukocytes. Here we review the role of CXCL4 and CXCL4L1 in cancer, the use of both chemokines as cancer biomarkers and discuss some possible therapeutic opportunities.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Cytokine - Volume 109, September 2018, Pages 65-71
نویسندگان
, , ,