Investigation of TGFβR2 SNP rs4522809, Osteopontin, TGF β1 and their association with dilatative pathology of ascending thoracic aorta

This is the first report on the association between previously defined TGFβR2 SNP rs4522809 linked with dilatation of ascending thoracic aorta. Also, for the first time we report the inversed correlation between circulating TGF-β1 and OPN concentrations in DPATA subjects indicating the possible biomarkers for DPATA.