کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8644831 | 1569769 | 2018 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Genome-wide identification and characterization of lncRNAs and miRNAs in cluster bean (Cyamopsis tetragonoloba)
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کلمات کلیدی
CPCSSRmiRNAsORFlncRNAsncRNAsETMFPKMFLCnon-coding RNAs - RNA های غیر کدگذاریMicro RNAs - RNA های میکروsimple sequence repeat - دنباله ساده تکرار کنیدopen reading frame - قاب خواندن بازFragments per kilobase of transcript per million mapped reads - قطعه در هر کیلو بایت رونویسی در هر میلیون نقشه برداری شده استCoding Potential Calculator - ماشین حساب پتانسیل کدگذاریFLOWERING LOCUS C - گل LOCUS C
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
ژنتیک
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Long non coding RNAs (lncRNAs) are a class of non-protein coding RNAs that play a crucial role in most of the biological activities like nodule metabolism, flowering time and male sterility. Quite often, the function of lncRNAs is species-specific in nature. Thus an attempt has been made in cluster bean (Cyamopsis tetragonoloba) for the first time to computationally identify lncRNAs based on a proposed index and study their targeted genes. Further, these targeted genes of lncRNAs were identified and characterized for their role in various biological processes like stress mechanisms, DNA damage repair, cell wall synthesis. Besides, lncRNAs and miRNAs bearing Simple Sequence Repeats (SSRs) were identified that contribute towards biogenesis of small non-coding RNAs. Moreover, five novel endogenous Target Mimic lncRNAs (eTMs) were identified that may disrupt the miRNA-mRNA regulations. For easy understanding and usability, a database CbLncRNAdb has been developed and made available at http://cabgrid.res.in/cblncrnadb.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gene - Volume 667, 15 August 2018, Pages 112-121
Journal: Gene - Volume 667, 15 August 2018, Pages 112-121
نویسندگان
Sarika Sahu, Atmakuri Ramakrishna Rao, Jaya Pandey, Kishor Gaikwad, Sabari Ghoshal, Trilochan Mohapatra,