کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8650736 1571136 2018 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Housing conditions modulate the reinforcing properties of cocaine in adolescent mice that binge on fat
ترجمه فارسی عنوان
شرایط مسکن باعث تقویت خواص تقویت کننده کوکائین در موش های نوجوانان می شود که از چربی ها چسبیده اند
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی فیزیولوژی
چکیده انگلیسی
Our results show a significant escalation in the consumption of a high-fat diet between the first and the last week in both types of housed mice. Among the grouped mice, only those exposed to high-fat binge (HFB) developed CPP. Conversely, isolated mice fed with standard diet were more sensitive to the rewarding effects of a subthreshold dose of cocaine than those fed with HFB. Plasma leptin levels were elevated in both groups that developed CPP. Although isolated animals presented higher corticosterone levels with respect to the grouped ones, anxiety levels did not differ. Therefore, our results highlight the importance of housing conditions on the effects that a high-fat diet exerts on cocaine reward.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Physiology & Behavior - Volume 183, 1 January 2018, Pages 18-26
نویسندگان
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