Parathyromatosis- Rare cause of recurrent hyperparathyroidism

Parathyromatosis is a rare cause of recurrent or persistent hyperparathyroidism. It poses great diagnostic and therapeutic challenge for the pathologist as well as the treating clinician. Parathyroid carcinoma remains a close clinical and histological diagnostic pitfall. We present a case of 44 year old woman who presented with persistent hypercalcemia and underwent multiple neck surgeries over a period of six years when she was finally diagnosed as parathyromatosis. There was also an incidental occurrence of papillary carcinoma of thyroid which is only rarely reported in literature.