کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8659796 1575728 2018 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Long Noncoding RNAs: New Players in Ischaemia-Reperfusion Injury
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Long Noncoding RNAs: New Players in Ischaemia-Reperfusion Injury
چکیده انگلیسی
Long noncoding RNAs (lncRNAs) constitute a new class of noncoding RNAs that interfere with gene expression. It has been shown that lncRNAs exert comprehensive effects on biological processes and are associated with numerous diseases such as cancer. However, the possible role of lncRNAs in ischaemia/reperfusion (I/R) injury have received relatively little attention. Accumulating evidence indicates that lncRNAs are also involved in the progression of I/R injury such as myocardial, cerebral, hepatic, renal and mesenteric I/R injury. In this review, we summarise the current knowledge of lncRNAs in I/R injury, attempting to better explain the molecular mechanism of I/R injury and provide new directions for its therapy.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Heart, Lung and Circulation - Volume 27, Issue 3, March 2018, Pages 322-332
نویسندگان
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