In vitro evaluation of clot capture efficiency of an absorbable vena cava filter

Conceptually, an absorbable inferior vena cava filter constructed from a flexible polymer is clinically appealing because it obviates filter retrieval and is unlikely to perforate the inferior vena cava and to impale neighboring organs. A recent in vivo study demonstrated that the investigational absorbable filter retained sufficient mechanical strength to function for the indicated prophylactic period with no migration, caval penetration, or tilt >15 degrees. This study assessed clot capture efficiency for the absorbable filter vs the Greenfield stainless steel filter as an indication of the filter's efficacy at preventing pulmonary embolism before commencement of human studies.