کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8680407 | 1579261 | 2017 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Variability in medication taking is associated with cognitive performance in nondemented older adults
ترجمه فارسی عنوان
متغیر بودن در مصرف دارو با عملکرد شناختی در بزرگسالان سالمند غیرمستقیم همراه است
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کلمات کلیدی
پایبندی به دارو، عملکرد شناختی، بزرگسالان سالمند، خانه هوشمند، نظارت مستمر،
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
عصب شناسی
چکیده انگلیسی
Interventions to slow cognitive decline typically can do little to reverse decline. Thus, early detection methods are critical. However, tools like cognitive testing are time consuming and require costly expertise. Changes in activities of daily living such as medication adherence may herald the onset of cognitive decline before clinical standards. Here, we determine the relationship between medication adherence and cognitive function in preclinical older adults. We objectively assessed medication adherence in 38 older adults (mean age 86.7 ± 6.9 years). Our results demonstrate that individuals with lower cognitive function have more spread in the timing of taking their medications (P = .014) and increase the spread in the timing of taking their medications over time (P = .012). These results demonstrate that continuous monitoring of medication adherence may provide the opportunity to identify patients experiencing slow cognitive decline in the earliest stages when pharmacologic or behavioral interventions may be most effective.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring - Volume 6, 2017, Pages 210-213
Journal: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring - Volume 6, 2017, Pages 210-213
نویسندگان
Johanna Austin, Krystal Klein, Nora Mattek, Jeffrey Kaye,