کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8685170 | 1580266 | 2018 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Symptom-associated change of motor-related neuromagnetic fields in a patient with multiple sclerosis: A case report
ترجمه فارسی عنوان
تغییرات مربوط به علائم مرتبط با زمینه های نورومغناطیسی مرتبط با موتور در بیمار مبتلا به مولتیپل اسکلروزیس: گزارش مورد
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کلمات کلیدی
بیماری دمیملین مغناطیس فوگلوگرافی، مولتیپل اسکلروزیس، میدان نئومغناطیسی، دمیلین شدن،
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
عصب شناسی
چکیده انگلیسی
The objective of this study was to investigate functional abnormalities of the brain in a patient with multiple sclerosis (MS) by using magnetoencephalography (MEG) and a finger-tapping task. A 46-year-old woman that presented with motor weakness of left hand and was diagnosed with MS. Conventional magnetic resonance imaging demonstrated a white matter lesion with hyperintensity on T2-weighted images in the right motor area. MEG recordings were performed during the period of motor weakness and after clinical improvement. Neuromagnetic brain activation was elicited by a simple, visually cued finger movement. The Equivalent current dipole (ECD) strength of the movement-evoked field (MEF) in the affected hemisphere was significantly decreased relative to the unaffected hemisphere. After improvement in motor weakness, we found that the lower amplitude of the readiness field and decreased ECD strength of the MEF observed in affected hemisphere during motor weakness had recovered. Analysis of motor-related neuromagnetic fields revealed that MEG may be used to detect diffuse changes in the brain that are not observable by conventional imaging of white matter regions in MS. We further found that brain activities can change after improvement in motor weakness.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Clinical Neuroscience - Volume 50, April 2018, Pages 115-122
Journal: Journal of Clinical Neuroscience - Volume 50, April 2018, Pages 115-122
نویسندگان
Ji Hee Kim, Bong Soo Kim, Su Jeong Hwang, Won Seok Chang, Ki Woong Kim, Hyuk Chan Kwon, Yong Ho Lee, Jin Woo Chang,