کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8685321 | 1580268 | 2018 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
MRI measurements of the normal pediatric optic nerve pathway
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موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
عصب شناسی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
The purpose of this work is to establish a reference scale of optic nerve pathway measurements in pediatric patients according to age using MRI. Optic nerve pathway measurements were retrospectively analyzed using an orbits equivalent sequence on brain MRI scans of 137 pediatric patients (72 male, 65 female, average ageâ¯=â¯7.7â¯years, standard deviationâ¯â¯=â¯5.3). The examinations were performed on a 1.5-T or 3-T Siemens MR system using routine imaging protocols. Measurements include diameters of the orbital optic nerves (OON), prechiasmatic optic nerves (PON), optic tracts (OT), and optic chiasm (OC). Measurements were performed manually by 2 neuroradiologists, using post-processing software. Patients were stratified into five age groups for measurement analyses: (I) 0-1.49â¯years, (II) 1.5-2.99â¯years, (III) 3-5.99â¯years, (IV) 6-11.99â¯years, and (V) 12-18â¯years. The observed value range of OON mean diameter was 2.7â¯mm (Interquartile range (IQR)â¯=â¯2.4-2.9), PON was 3.2â¯mm (IQRâ¯â¯=â¯â¯3.05-3.5), OT 2.6â¯mm (IQRâ¯=â¯2-2.9). A strong positive correlation was established between age and mean diameter of OON (râ¯=â¯0.73, pâ¯<â¯.001), PON (râ¯=â¯0.59, pâ¯<â¯.001), and OT (râ¯=â¯0.72, pâ¯<â¯.001). A significant difference in mean OON diameters was found between age groups I-II (dâ¯=â¯0.3, pâ¯=â¯.01), II-III (dâ¯=â¯0.5, pâ¯<â¯.001), III-IV (dâ¯=â¯0.5, pâ¯<â¯.001) followed by a plateau between IV-V (dâ¯=â¯0.l0, pâ¯=â¯.19). OON/OT ratio maintained a steady mean value 1 (IQRâ¯=â¯0.93-1.1) regardless of age (pâ¯=â¯.7). The diameter of optic pathways was found to increase as a function of age with consistent positive correlation between nerve and tract for all ages.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Clinical Neuroscience - Volume 48, February 2018, Pages 209-213
Journal: Journal of Clinical Neuroscience - Volume 48, February 2018, Pages 209-213
نویسندگان
Hillel S. Maresky, Anna Ben Ely, Tatyana Bartischovsky, Judith Coret-Simon, Yair Morad, Simon Rozowsky, Miriam Klar, Saida Negieva, Inessa Bekerman, Sigal Tal,