کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8685494 1580270 2017 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Factors associated with early dramatic recovery following successful recanalization of occluded artery by endovascular treatment in anterior circulation stroke
ترجمه فارسی عنوان
عوامل موثر در بهبود زودرس پس از پیگیری موفقیت آمیز سرنگ انسداد توسط درمان آندوسکوپی در سکته مغزی گردنی
کلمات کلیدی
بازیابی سریع دراماتیک، بازنگری درمان آندوسکوکال، بهبود عمده عصبی،
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
چکیده انگلیسی
Endovascular treatment (EVT) significantly increases the recanalization rate and improves functional outcomes in acute ischemic stroke. However, despite successful recanalization by EVT, some stroke patients demonstrate no early dramatic recovery (EDR). We assessed factors associated with EDR following recanalization by EVT. We included subjects with anterior circulation stroke treated with EVT who met the following criteria: Thrombolysis in Cerebral Ischemia scores (TICI) 2b-3 after EVT, lesion volume <70 mL as seen on the pre-treatment diffusion-weighted imaging (DWI) scan and a baseline NIHSS score ≥6. EDR was defined as a ≥8-point reduction in the NIHSS score, or NIHSS score of 0 or 1 measured 24 h following treatment. Multivariate regression analyses were performed to identify the predictors associated with EDR. Of the 102 patients (mean age, 64.3 years; median National Institutes of Health Stroke Scale score, 14), EDR was achieved in 39 patients (38.2%). The median DWI lesion volume was 12 mL (interquartile range, 5-25 mL). Median onset-to-recanalization time in these patients was 320 min (interquartile range, 270-415 min). Logistic regression analysis identified a higher initial NIHSS score (OR 1.17, 95% CI 1.03-1.33, P = 0.016) and shorter time from onset to recanalization (OR 0.99, 95% CI 0.986-0.997, P = 0.003), to be independently associated with EDR. In the setting of pretreatment DWI lesion volume <70 mL, a higher initial NIHSS score and faster time from onset to recanalization may be important predictors of EDR following successful EVT.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Clinical Neuroscience - Volume 46, December 2017, Pages 171-175
نویسندگان
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