کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8687574 1580947 2018 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Exploring the prediction of emotional valence and pharmacologic effect across fMRI studies of antidepressants
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی روانپزشکی بیولوژیکی
پیش نمایش صفحه اول مقاله
Exploring the prediction of emotional valence and pharmacologic effect across fMRI studies of antidepressants
چکیده انگلیسی
We found limited evidence that antidepressants modulated brain response in a consistent manner, however found a consistent signature for emotional valence. Variable functional patterns across studies suggest that predictive modeling can inform biomarker development in mental health and in pharmacotherapy development. Our results suggest that case-controlled designs and more standardized protocols are required for functional imaging to provide robust biomarkers for drug development.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: NeuroImage: Clinical - Volume 20, 2018, Pages 407-414
نویسندگان
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