Electro-clinical expression and pharmaco-therapeutic options in Jeavons syndrome-case report and review of literature

Jeavons syndrome (JS) is a well known but under reported epilepsy syndrome characterized by distinct clinical and electrographic features. In a 10 year old boy with atypical absences, a videotelemetry was performed and the findings are narrated to illustrate the spectrum of abnormalities in JS, comprising of eye closure induced paroxysms of epileptiform discharges,focal and generalized spike and wave discharges, occipital intermittent rhythmic delta activity and photopraoxysmal response. The report also discusses the therapeutic strategies employed, especially the addition of zonisamide as a very effective first add−on. In conclusion, this case report is an attempt to briefly explore the manifold aspects of this uncommon epilepsy syndrome especially the clinical and electrographic presentations and treatment strategies.