Study of acute hypoxia markers in healthy subjects: Utility in post-crash investigation

Our study reveals that HIF-1α and EPO are sensitive to hypoxia exposure as compared to lactic acid and can be used in association with LA as hypoxia markers. However stability of these proteins in postmortem conditions needs to be studied and the potential for estimation of mRNA transcripts of HIF-1α and EPO, which would be stable in postmortem conditions, can be explored.