Synthesis and antibacterial activity of N-pyridin-2-ylbenzenesulfonamide nanoparticles

Sulfonamide nanoparticles were prepared by reacting benzenesulfonyl chloride with amine groups present in acetonitrile solvent. Ultrasonic treatment was applied for preparation of the sulfonamide nanoparticles. The produced sulfonamide nanoparticles were characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM) and other techniques. The antibacterial activity of sulfonamide nanoparticles was tested against microorganism and compared with microscale sulfonamide antibacterial properties.