کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8707765 | 1586340 | 2018 | 40 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Multiple primary squamous cell carcinomas of the lower lip and tongue arising in discoid lupus erythematosus: a case report
ترجمه فارسی عنوان
کارسینومای اولیه سلول سنگفرشی اولیه لب پایین و زبان ناشی از لوپوس اریتماتوس دیسویود: گزارش مورد
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موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
دندانپزشکی، جراحی دهان و پزشکی
چکیده انگلیسی
Squamous cell carcinoma (SCC) developing in lesions of discoid lupus erythematosus (DLE) is rare, most frequently arising on sun-exposed skin and very rarely affecting the lips. A review of the English language literature revealed only 21 published cases of labial SCC in patients with DLE. Here, an unusual case of a patient with DLE who developed 3 primary SCCs of the oral and perioral region is presented. A 40-year-old female with a 24-year history of DLE with peri- and intraoral involvement initially developed SCC of the vermillion border of the right lower lip; the lesion was surgically removed and did not recur within 6 months. In spite of strong recommendation for regular follow-up, the patient failed to keep her appointments but returned 7 years later. No signs of recurrence of the original lower lip cancer were noticed, but a new SCC of the left lateral border of the tongue with cervical lymph node metastasis was diagnosed; despite aggressive combined treatment, locoregional recurrence and distant metastatic disease developed within a few months; in addition, a new primary SCC of the vermillion border of the left lower lip developed. This rare case and a thorough review of the pertinent literature underscore the possibility of development of even multiple intraoral and perioral SCCs in the context of longstanding DLE, which necessitates close long term follow-up for early diagnosis and management.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - Volume 125, Issue 2, February 2018, Pages e22-e30
Journal: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - Volume 125, Issue 2, February 2018, Pages e22-e30
نویسندگان
Ioanna-Eirini DDS, MSc, Nikolaos G. MD, DDS, PhD, Maria DDS, MSc, PhD, Nick MD, DDS, MSc, PhD, Athanasios MD, PhD, Alexandra DDS, MSc, PhD,