کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
871032 1471040 2009 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A Multi-channel platform for recording and stimulation of large neuronal structures
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مهندسی پزشکی
پیش نمایش صفحه اول مقاله
A Multi-channel platform for recording and stimulation of large neuronal structures
چکیده انگلیسی

In order to understand the dynamics of large neural networks, where information is widely distributed over thousands of cells, one of today's challenges is to successfully record the simultaneous activities of as many neurons as possible. This is made possible by using microelectrodes arrays (MEA) positioned in contact with the neural tissue. Thanks to microelectronics’ microfabrication technologies, it now becomes possible to build high-density MEA containing several hundreds of microelectrodes. However, increasing the number of electrodes using conventional electronics is difficult to achieve. Moreover, high-density devices addressing all channels independently for simultaneous recording and stimulation are not readily available. Here, we present a 256-channel in vitro MEA data acquisition system with integrated electronics allowing simultaneous recording and stimulation of neural networks for in vitro and in vivo applications. This integration is a first step towards an implantable device for a neural prosthesis.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: IRBM - Volume 30, Issues 5–6, November–December 2009, Pages 226–233
نویسندگان
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