کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8712455 1587053 2018 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Neonatal lupus erythematosus presenting as Stevens-Johnson syndrome
ترجمه فارسی عنوان
لوپوس اریتماتوز نوزادی که به عنوان سندرم استیونز-جانسون معرفی شده است
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی امراض پوستی
چکیده انگلیسی
Neonatal lupus erythematosus (NLE) is a rare acquired condition caused by the transplacental passage of maternal autoantibodies. It is characterized by cutaneous, cardiac, hepatobiliary, hematological and neurological involvement. Cutaneous findings of NLE are variable, but few reports in the literature describe the presence of erosions or epidermal loss in NLE. Herein, we describe the case of an infant with NLE presenting as Stevens-Johnson syndrome (SJS), with cardiac, hematologic, hepatobiliary and neurologic abnormalities. The characteristic features by which to differentiate SJS-like NLE from infant SJS include subacute course, cardiac abnormalities, positive serology tests and direct immunofluorescence, histopathologic findings with melanin incontinence, periadnexal infiltrates, and mucin deposit. Though rare, it is important to consider lupus erythematosus as a potential cause of acute syndrome with focal epidermal necrosis or pan-epidermolysis.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Dermatologica Sinica - Volume 36, Issue 2, June 2018, Pages 97-100
نویسندگان
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