کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8742772 | 1592506 | 2017 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Fibrosis angiocéntrica eosinofÃlica intranasal asociada a enfermedad relacionada con IgG4
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
ایمونولوژی، آلرژی و روماتولوژی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Eosinophilic angiocentric fibrosis is an uncommon tumefactive lesion of the ocular orbit and upper respiratory tract. We present a 44-year old man with a history of severe nasal congestion and nasal obstruction. The patient also reported symptoms of sinusitis. Submucous thickening tissue had been locally resected and the involved anterior nasal septum cartilage partially removed. Histopathological examination of the biopsy indicated eosinophilic angiocentric fibrosis. A CT scan of the sinuses showed a high-density focal mass of soft tissue arising from the anterior aspect of the nasal septum. Examination under low power view showed dense concentric fibrosis and mixed inflammatory cells. The fibrosis was in an angiocentric pattern, resembling an onionskin. High power view showed a mixture of lymphocytes, plasma cells, numerous eosinophils, and proliferating fibroblasts. A test for serum IgG performed ten years after the patient's initial presentation was 1421Â mg/dl (normal range 540-1822Â mg/dl), and the serum concentration of IgG4 was 168.70Â mg/dl (normal range 6.1-121Â mg/dl). A review of the original haematoxylin and eosin-stained slides revealed that this case was stained immunohistochemically with an IgG4 stain showing 50 IgG4-positive plasma cells/HPF.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Revista Colombiana de ReumatologÃa - Volume 24, Issue 3, JulyâSeptember 2017, Pages 189-192
Journal: Revista Colombiana de ReumatologÃa - Volume 24, Issue 3, JulyâSeptember 2017, Pages 189-192
نویسندگان
Jesica Gallo, Cecilia Pisoni, Daniel González Cueto, John H. Stone, Sergio Paira,