Quoi de neuf en allergologie pédiatrique de fin 2015Â Ã début 2018Â ? Anaphylaxie, allergie médicamenteuse et aux venins et salives d'insectes (une revue de la littérature internationale)

Most interesting findings are as follows: clinical symptoms of anaphylaxis are not similar in older children (cardiovascular) and younger ones (gastro-intestinal and respiratory) in whom sudden occurrence of such symptoms should evoke anaphylaxis; first cases of anaphylaxis to exotic foods (crocodile, natto, etc.) have been published and will probably increase during near future; prolonged provocation tests should precede skin and in vitro tests in children reporting non-immediate and non-severe reactions to beta-lactams; allergic hypersensitivity to non-steroidal anti-inflammatory drugs is probably more frequent in children than in adults, in whom most reactions are non-allergic; local reactions to vaccines are relatively frequent and reccur frequently, but are benign-moderately severe. In contrast, generalized reactions are rare and relapses are infrequent, except for immediate anaphylactic reactions; hemagglutinins of influenza viruses (influenza vaccines) and toxoids in conjugated vaccines (pneumococcal) may induce anaphylactic reactions; mast cell diseases may be a risk of vaccine-induced anaphylaxis; as well as mosquito « allergy », hymenoptera venom allergy resolve spontaneously in children reporting mild to moderately severe generalized reactions to hymenoptera stings; in children reporting severe reactions to hymenoptera stings, specific immunotherapy is efficient, but efficiency decreases with age and patients may have anaphylaxis when restung several years after the end of immunotherapy.