کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
874726 910347 2008 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Model-generated decomposition of unfused tetani of motor units evoked by random stimulation
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مهندسی پزشکی
پیش نمایش صفحه اول مقاله
Model-generated decomposition of unfused tetani of motor units evoked by random stimulation
چکیده انگلیسی

Unfused tetani of motor units (MUs) evoked by stimulation at variable interpulse intervals at mean frequencies of 20, 25, 33, 40 and 50 Hz were studied using ten functionally isolated fast-type MUs from the medial gastrocnemius muscle of adult Wistar rats. A previously proposed algorithm and computer program for mathematical decomposition of unfused tetani into a series of twitches, representing responses to individual pulses, were used. Analysis of the parameters of the decomposed twitches showed considerable variability in force of successive contractions. These twitches were extremely variable with up to 2-fold higher forces and longer contraction times than a single twitch evoked by one stimulus. However, when the stimulation frequency was decreased, the decomposed twitches became similar to the single twitch with respect to amplitude and contraction time. It was found that the basic contractile parameters of decomposed twitches could be predicted with high accuracy on the basis of the tetanus force level at which the next contraction begins. This analysis of the parameters of decomposed twitches demonstrated that the contractile responses of the muscle fibers to successive action potentials generated by motoneurons are highly variable and depend on the previous MU state.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Biomechanics - Volume 41, Issue 16, 5 December 2008, Pages 3448–3454
نویسندگان
, , , , , ,