کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
874972 910357 2008 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Remodeling of conduit arteries in hypertension and flow-overload obeys a minimum energy principle
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مهندسی پزشکی
پیش نمایش صفحه اول مقاله
Remodeling of conduit arteries in hypertension and flow-overload obeys a minimum energy principle
چکیده انگلیسی

Arterial remodeling is an important process in physiology and pathophysiology. Based on an energy minimization method, Murray's law predicts the optimal inner radius. Application of Darcy's law in the wall results in an optimal outer radius. The average wall stress is computed by the Laplace's law. Using these formulas, a large porcine coronary artery in hypertension is studied. The results reveal how wall thickness and average circumferential stress change after increasing blood pressure and volume flow rate. The theoretical predictions are in good qualitative agreement with experimental observations. The advantage and limitation of the current approach are discussed.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Biomechanics - Volume 41, Issue 11, 7 August 2008, Pages 2567–2570
نویسندگان
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