کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
875157 910363 2008 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
CFD analysis of pulsatile blood flow in an atherosclerotic human artery with eccentric plaques
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مهندسی پزشکی
پیش نمایش صفحه اول مقاله
CFD analysis of pulsatile blood flow in an atherosclerotic human artery with eccentric plaques
چکیده انگلیسی

Atherosclerosis is a slow vascular degeneration. It thickens the internal walls of a blood vessel locally depositing an atherosclerotic plaque. Such reduced lumen increases the resistance to blood flow. Plaques can be punctual (eccentric, here considered) or circumferential (symmetrical). Stenoses do not have a typical shape: we hypothesised here a reference geometry (trapezium) with its possible evolutions (semi-ellipse, triangle). Two criteria (Equivalent Area and Equivalent Dimensions) were then defined to compare the results among the 35 case studies numerically analysed with a Computational Fluid Dynamics code (Comsol Multiphysics 3.3). Blood was considered a Cassonian fluid with modified viscosity equation. The artery was cylindrical, rigid and straight, interested by a pulsatile blood flow. Among the variables: shape and dimensions of the stenoses; number of stenoses (single or coupled pathologies); mutual locations (3 possibilities). The main results were that the length of the consequent flow disturbance is due to the stenotic shape and height; blood flow recirculation, downstream of the pathology, is due to the slope of the stenotic walls; and the peak velocities depend on the shape and height of stenosis. The differences from case to case diminish in diastole.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Biomechanics - Volume 41, Issue 9, 2008, Pages 1862–1870
نویسندگان
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