Rise of mosquito bites in India: A comprehensive study on dengue

Globally, dengue has become one of the major public health concerns. However, the threat of dengue virus (DENV) has been overlooked due to lack of continuous surveillance. The four DENV serotypes are the reason for this serious illness and for its treatment till date no commercial drug is available. The increase in demand of plant based medicine and lack of anti-dengue drug and therapy has triggered to review available literature of potential anti-dengue plants against DENV serotypes. Therefore, the twin objective of this study aims to explore the current dengue data in India (2011-2016) and to review potential anti-dengue plants for their inhibition activity on DENV serotypes. Dengue data from time period 2011-2016 has been reviewed and analysed state, region and year wise in India and studies from 2002-2016 related to potential anti-dengue plant have been reviewed for their inhibition activity on DENV serotypes. It was observed that Tamil Nadu, Kerala, Gujarat, West Bengal, Maharashtra and Karnataka are highly and most consistently affected states. South region of India, most affected by DENV and 2015, 2013 reported the highest number of dengue cases. Moreover, the reviewed potential anti-dengue plants majorly show inhibition activity against DENV 2. Study revealed the current scenario of DENV and identified the largely affected areas and regions in India for development of health initiatives and future studies are encouraged to identify plant species showing inhibition activity against DENV 3, 4.