کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8754109 | 1595989 | 2017 | 50 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Medicinal plant products targeting quorum sensing for combating bacterial infections
ترجمه فارسی عنوان
محصولات گیاهان دارویی که برای کنترل عفونت های باکتریایی هدف گیری می کنند
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کلمات کلیدی
سنجش قاعده، بیوفیلم ها، مقاومت باکتریایی، ترکیبات طبیعی،
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
پزشکی و دندانپزشکی (عمومی)
چکیده انگلیسی
Traditional treatment of infectious diseases is based on compounds that aim to kill or inhibit bacterial growth. The bacterial resistance against antibiotics is a serious issue for public health. Today, new therapeutic targets other than the bacterial wall were deciphered. Quorum sensing or bacterial pheromones are molecules called auto-inducer secreted by bacteria to regulate some functions such as antibiotic resistance and biofilms formation. This therapeutic target is well-studied worldwide, nevertheless the scientific data are not updated and only recent researches started to look into its potential as a target to fight against infectious diseases. A major concern with this approach is the frequently observed development of resistance to antimicrobial compounds. Therefore, this paper aims to provide a current overview of the quorum sensing system in bacteria by revealing their implication in biofilms formation and the development of antibiotic resistance, and an update on their importance as a potential target for natural substances.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Asian Pacific Journal of Tropical Medicine - Volume 10, Issue 8, August 2017, Pages 729-743
Journal: Asian Pacific Journal of Tropical Medicine - Volume 10, Issue 8, August 2017, Pages 729-743
نویسندگان
Abdelhakim Bouyahya, Nadia Dakka, Abdeslam Et-Touys, Jamal Abrini, Youssef Bakri,