Cystic fibrosis transmembrane conductance regulator in the endolymphatic sac of the rat

RT-PCR and immunohistochemistry were used to identify the expression of CFTR in the endolymphatic sac epithelia, which gives us a clue for understanding Cl− transport in the endolymphatic sac. These results suggest a pathway for Cl−, possibly through interaction with the ENaC, which may regulate the endolymph in the endolymphatic sac.