Nontypeable Haemophilus influenzae isolated from intractable acute otitis media internalized into cultured human epithelial cells

The potential of NTHi as the intracellular pathogen may contribute to the persistent existence of this pathogen that result in the prolonged and intractable clinical course of AOM. Azithromycin may be a therapeutically significant antibiotic for patients with prolonged respiratory tract infections due to NTHi.